I am a winning player at PLO8 with a win rate of 9 PTBB/100 hands and a standard deviation of 55 PTBB/100 hands over a sample size of 65000 hands and my largest downswing in PLO8 so far has been 12.5 buy-ins and the second largest 8 buy-ins. Based on my experience you should probably play with a 15 buy-in bankroll.
Good professional poker players usually need a bankroll of at least 300 times the big bet, when playing in Limit game. Also your playing style affects the size of your bank roll. The looser you play (can still be a good way of playing) and the more loose/aggressive games you participate in, the bigger will the swings in your bank roll be.
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